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DOI: 10.1055/s-0043-119212
Magnified endoscopic observation of small depressed gastric lesions using linked color imaging with indigo carmine dye
Publikationsverlauf
submitted 16. Februar 2017
accepted after revision 04. August 2017
Publikationsdatum:
27. September 2017 (online)
![](https://www.thieme-connect.de/media/endoscopy/201802/lookinside/thumbnails/15410_10-1055-s-0043-119212-1.jpg)
Abstract
Background and study aims Magnifying linked color imaging with indigo carmine dye (M-Chromo-LCI) enables sterically enhanced and color image-magnified observation of the superficial gastric mucosa. This study investigated the usefulness of M-Chromo-LCI for the differential diagnosis of gastric lesions.
Patients and methods 100 consecutive small depressed lesions were examined with conventional white-light imaging (C-WLI), magnifying blue-laser imaging (M-BLI), and M-Chromo-LCI. Endoscopic images were reviewed by three experts and three non-experts. Diagnostic accuracy and interobserver agreement were compared among the modalities.
Results For experts, M-BLI showed a significantly higher diagnostic accuracy than C-WLI (82.7 % vs. 67.0 %; P < 0.001). The diagnostic accuracy of M-Chromo-LCI was not different from M-BLI (87.7 % vs. 82.7 %; P = 0.31). For non-experts, M-BLI showed a significantly higher diagnostic accuracy than C-WLI (69.3 % vs. 52.3 %; P < 0.001). M-Chromo-LCI additionally showed a significantly higher diagnostic accuracy than M-BLI (79.7 % vs. 69.3 %; P = 0.005). M-Chromo-LCI had the highest interobserver agreement for each group.
Conclusions: M-Chromo-LCI is expected to become a useful modality for the accurate diagnosis of gastric lesions.
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