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CC BY 4.0 · Journal of Health and Allied Sciences NU 2024; 14(01): 141-145
DOI: 10.1055/s-0043-1766124
Case Report

Intracholecystic Papillary Neoplasm of Gallbladder in a Middle-Aged Woman—A Rare Entity

Shubha Padmanabha Bhat 
1   Department of Pathology, KS Hegde Medical Academy, Nitte (Deemed to be University), Deralakatte, Mangalore, Karnataka, India
,
Sreelakshmi Abhiram
1   Department of Pathology, KS Hegde Medical Academy, Nitte (Deemed to be University), Deralakatte, Mangalore, Karnataka, India
,
Srinivas Teerthanath
1   Department of Pathology, KS Hegde Medical Academy, Nitte (Deemed to be University), Deralakatte, Mangalore, Karnataka, India
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Abstract

Intracholecystic papillary neoplasm of the gallbladder is a rare and relatively new entity in the fifth edition of the World Health Organization classification of tumors of the digestive system. It mainly occurs in elderly women. It is an exophytic, granular, and friable mass seen in gallbladder mucosa, often mistaken clinically as sludge. We report a middle-aged female with abdominal pain and a vague mass in the right hypochondrium. A computed tomography scan of the abdomen and pelvis showed a heterogeneously enhancing lesion in the gallbladder lumen extending from the fundus to the neck, causing an irregular luminal obstruction. Histopathological examination of the cholecystectomy specimen showed features of intracholecystic papillary neoplasm of biliary and oncocytic type with low-grade dysplasia.

Keywords

intracholecystic papillary neoplasm - gallbladder - histopathology


Publikationsverlauf

Artikel online veröffentlicht:
14. April 2023

© 2023. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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  • References

  • 1 Bosman F. WHO Classification of Tumors of the Digestive system. 5th ed. Lyon: International Agency for Research on Cancer; 2010: 276-278
    Suche in Google Scholar
  • 2 Chatterjee A, Lopes Vendrami C, Nikolaidis P. et al. Uncommon intraluminal tumors of the gallbladder and biliary tract: spectrum of imaging appearances. Radiographics 2019; 39 (02) 388-412
    CrossrefPubMedSuche in Google Scholar
  • 3 Nakanuma Y, Nomura Y, Watanabe H. et al. Pathological characterization of intracholecystic papillary neoplasm: a recently proposed preinvasive neoplasm of gallbladder. Ann Diagn Pathol 2021; 52: 151723
    CrossrefPubMedSuche in Google Scholar
  • 4 Muranushi R, Saito H, Matsumoto A. et al. A case report of intracholecystic papillary neoplasm of the gallbladder resembling a submucosal tumor. Surg Case Rep 2018; 4 (01) 124-128
    CrossrefPubMedSuche in Google Scholar
  • 5 Adsay V, Jang KT, Roa JC. et al. Intracholecystic papillary-tubular neoplasms (ICPN) of the gallbladder (neoplastic polyps, adenomas, and papillary neoplasms that are ≥1.0 cm): clinicopathologic and immunohistochemical analysis of 123 cases. Am J Surg Pathol 2012; 36 (09) 1279-1301
    CrossrefPubMedSuche in Google Scholar
  • 6 Hazarika P, Sharma MK. Intracholecystic papillary-tubular neoplasm of gallbladder: a 5-year retrospective pathological study. Indian J Pathol Microbiol 2018; 61 (04) 516-519
    CrossrefPubMedSuche in Google Scholar
  • 7 Yokode M, Hanada K, Shimizu A. et al. Intracholecystic papillary neoplasm of the gallbladder protruding into the common bile duct: a case report. Mol Clin Oncol 2019; 11 (05) 488-492
    PubMedSuche in Google Scholar
  • 8 Michalinos A, Alexandrou P, Papalambros A. et al. Intracholecystic papillary-tubular neoplasm in a patient with choledochal cyst: a link between choledochal cyst and gallbladder cancer?. World J Surg Oncol 2016; 14 (01) 202
    CrossrefPubMedSuche in Google Scholar