CC BY 4.0 · Journal of Health and Allied Sciences NU 2024; 14(03): 431-435
DOI: 10.1055/s-0043-1772743
Case Report

Hypereosinophilia Syndrome: Myriad Presentation—A Case Report

Mansi Patel
1   Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research (Deemed to be university), Maharashtra, India
,
Divit Shah
1   Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research (Deemed to be university), Maharashtra, India
,
Sujal Patel
1   Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research (Deemed to be university), Maharashtra, India
,
Sourya Acharya
1   Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research (Deemed to be university), Maharashtra, India
,
Sunil Kumar
1   Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research (Deemed to be university), Maharashtra, India
,
Samarth Shukla
2   Department of Pathology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research (Deemed to be university), Maharashtra, India
› Author Affiliations

Abstract

Hypereosinophilic syndrome is a myeloproliferative disorder that is distinguished with the presence of eosinophilia, which is an absolute eosinophil level of more than 1500/µL for no less than 6 months, no recognized cause for eosinophilia, and clear organ involvement characteristics. But, in some cases where patients require therapy to decrease eosinophil counts due to severe symptoms, a lower time period of hypereosinophilic is also admissible. In this case series, we have included three cases in which first case presented with the features of diarrhea, nausea, and decreased appetite who underwent colonoscopy and was diagnosed as a case of eosinophilic colitis. The second patient was a female came with abdominal pain and burning micturition, who was having eosinophilia on blood count examination and was diagnosed as a case of eosinophilic cystitis. Third case was young female who was diagnosed as eosinophilic endocarditis on two-dimensional echocardiography having dyspnea and rash and high eosinophil count on blood smear. All the three patients were started on steroids, who recovered well with medication and were discharged for follow-up after 7 days with complete blood count.



Publication History

Article published online:
24 August 2023

© 2023. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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  • References

  • 1 Klion A. Hypereosinophilic syndrome: current approach to diagnosis and treatment. Annu Rev Med 2009; 60: 293-306
  • 2 Straumann A. Idiopathic eosinophilic gastrointestinal diseases in adults. Best Pract Res Clin Gastroenterol 2008; 22 (03) 481-496
  • 3 Neeman A, Shoenfeld Y, Eldar M, Delpre G, Leisser A, Pinkhas J. [Eosinophilic gastroenteritis]. Harefuah 1978; 95 (3-4) 108
  • 4 Shehwaro N, Langlois AL, Gueutin V, Izzedine H. Renal involvement in idiopathic hypereosinophilic syndrome. Clin Kidney J 2013; 6 (03) 272-276
  • 5 Kumar S, Diwan SK, Chillawar S, Shabarwal S, Goyal S, Jain S. Wegener's granulomatosis with peripheral eosinophilia in a young adult patient. J Med 2013; 14 (02) 204-206
  • 6 Khoury P, Makiya M, Klion AD. Clinical and biological markers in hypereosinophilic syndromes. Front Med (Lausanne) 2017; 4: 240
  • 7 Dulohery MM, Patel RR, Schneider F, Ryu JH. Lung involvement in hypereosinophilic syndromes. Respir Med 2011; 105 (01) 114-121
  • 8 Valent P, Klion AD, Horny HP. et al. Contemporary consensus proposal on criteria and classification of eosinophilic disorders and related syndromes. J Allergy Clin Immunol 2012; 130 (03) 607-612.e9
  • 9 Cheung CC, Constantine M, Ahmadi A, Shiau C, Chen LYC. Eosinophilic myocarditis. Am J Med Sci 2017; 354 (05) 486-492
  • 10 Crane MM, Chang CM, Kobayashi MG, Weller PF. Incidence of myeloproliferative hypereosinophilic syndrome in the United States and an estimate of all hypereosinophilic syndrome incidence. J Allergy Clin Immunol 2010; 126 (01) 179-181