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CC BY 4.0 · Journal of Health and Allied Sciences NU 2024; 14(03): 400-404
DOI: 10.1055/s-0043-1775844
Original Article

Evaluation of Drug Utilization and Dose Intensity Pattern in Dyslipidemic Patients with Type 2 Diabetes Mellitus

Abdul Safwan
1   Department of Pharmacy Practice, NGSM Institute of Pharmaceutical Sciences (NGSMIPS), Nitte (Deemed to be University), Mangalore, Karnataka, India
,
Suresh G.
2   Department of General Medicine, K.S. Hegde Medical Academy (KSHEMA), Nitte (Deemed to be University), Mangalore, Karnataka, India
,
Bipin Shaji 
1   Department of Pharmacy Practice, NGSM Institute of Pharmaceutical Sciences (NGSMIPS), Nitte (Deemed to be University), Mangalore, Karnataka, India
,
Srinitha Sridhar 
1   Department of Pharmacy Practice, NGSM Institute of Pharmaceutical Sciences (NGSMIPS), Nitte (Deemed to be University), Mangalore, Karnataka, India
,
Reshma Kolar
3   Department of Biostatistics, K.S. Hegde Medical Academy (KSHEMA), Nitte (Deemed to be University), Mangalore, Karnataka, India
,
Juno Jerold Joel 
1   Department of Pharmacy Practice, NGSM Institute of Pharmaceutical Sciences (NGSMIPS), Nitte (Deemed to be University), Mangalore, Karnataka, India
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Abstract

Dyslipidemia can increase the risk of cardiovascular disease in individuals with metabolic diseases. Patients may have to take multiple medications simultaneously, leading to polypharmacy. A retrospective study was conducted to evaluate drug utilization and dose intensity patterns in dyslipidemic patients with type 2 diabetes mellitus over an 8-month period at a tertiary care hospital. The study included the case sheets of patients diagnosed with dyslipidemia and type 2 diabetes. The required data for the study were collected from the patient's case sheets from the Medical Records Department (from June 2015 to May 2020). The data were documented using MS Excel 2013 and analyzed descriptively using SPSS software version 20. Among the 384 study population, 53% were males and 47% were females, with an age group of 45 to 59 years. Metformin and glimepiride were the most commonly prescribed oral hypoglycemic agents, while glibenclamide was the least prescribed. Atorvastatin was the most prescribed hypolipidemic agent. The combination of atorvastatin and fenofibrate was the most preferred combination therapy. The most frequently prescribed hypoglycemic and hypolipidemic agents were metformin and atorvastatin, respectively. Dyslipidemic patients with diabetes mellitus require the administration of multiple medications. It is crucial to monitor medication adherence and medication-related problems among these populations.

Keywords

drug utilization - dyslipidemia - type 2 diabetes mellitus - medication adherence

Ethical Approval

The study was approved by the Institutional Ethics Committee, NGSM Institute of Pharmaceutical Sciences, Nitte (Deemed to be University), Karnataka, India (Ref No: NGSMIPS/IEC/11/2021).




Publication History

Article published online:
08 November 2023

© 2023. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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