PDF herunterladen
CC BY 4.0 · Journal of Health and Allied Sciences NU 2024; 14(04): 566-569
DOI: 10.1055/s-0043-1777020
Case Report

Hepatocellular Carcinoma Presenting as Extension of Tumor Thrombus into the Right Atrium from the Portal Vein through Inferior Vena Cava Treated with Chemoembolization: A Rare Case Report

Kashish Khurana
1   Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research (Deemed to be University), Sawangi (Meghe), Wardha, Maharashtra, India
,
Saket Toshniwal 
1   Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research (Deemed to be University), Sawangi (Meghe), Wardha, Maharashtra, India
,
Nikhil Pantbalekundri
1   Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research (Deemed to be University), Sawangi (Meghe), Wardha, Maharashtra, India
,
Sunil Kumar
1   Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research (Deemed to be University), Sawangi (Meghe), Wardha, Maharashtra, India
,
Sourya Acharya
1   Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research (Deemed to be University), Sawangi (Meghe), Wardha, Maharashtra, India
› Institutsangaben
› Weitere Informationen
Auch verfügbar auf
   Lizenzen und Reprints

Abstract

Patients with tumor thrombosis in the portal vein due to hepatocellular carcinoma (HCC) are uncommon, and the majority of these cases is thought to be in an advanced stage with a bad prognosis. The right atrium and the inferior vena cava may be impacted by the intravascular tumor thrombus, with the latter having a bad prognosis. Portal vein involvement is one of the most serious consequences of HCC. For both systemic and locoregional therapy, targeting many pathways in the HCC cascade using a mix of medications and additional modalities like transarterial chemoembolization, transarterial radioembolization, radiation, and hepatic arterial infusion chemotherapy appears to be helpful.

Portal vein tumor thrombosis, which affects 35 to 50% of patients, is a strong predictor of poor prognosis due to the higher likelihood of tumor migration into the bloodstream and the subsequent increased risk of recurrence. This case report highlights about a 60-year-old female who presented with HCC with portal vein tumor thrombosis not willing for chemo- and radiotherapy successfully treated with transarterial chemoembolization as a palliative management.

Keywords

tumor thrombosis - right atrium - transarterial chemoembolization - transarterial radioembolization


Publikationsverlauf

Artikel online veröffentlicht:
22. November 2023

© 2023. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

 

  • References

  • 1 Md Radzi AB, Tan SS. A case report of metastatic hepatocellular carcinoma in the mandible and coracoid process: a rare presentation. Medicine (Baltimore) 2018; 97 (04) e8884
    CrossrefPubMedSuche in Google Scholar
  • 2 Luo X, Zhang B, Dong S, Zhang B, Chen X. Hepatocellular carcinoma with tumor thrombus occupying the right atrium and portal vein: a case report and literature review. Medicine (Baltimore) 2015; 94 (34) e1049
    CrossrefPubMedSuche in Google Scholar
  • 3 Gomez-Puerto D, Mirallas O, Vidal-González J, Vargas V. Hepatocellular carcinoma with tumor thrombus extends to the right atrium and portal vein: a case report. World J Hepatol 2020; 12 (11) 1128-1135
    CrossrefPubMedSuche in Google Scholar
  • 4 Fujii T, Takayasu K, Muramatsu Y. et al. Hepatocellular carcinoma with portal tumor thrombus: analysis of factors determining prognosis. Jpn J Clin Oncol 1993; 23 (02) 105-109
    PubMedSuche in Google Scholar