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DOI: 10.1055/s-0044-101453
Initial experience with a novel resection and plication (RAP) method for acid reflux: a pilot study
Publication History
submitted 21 October 2017
accepted after revision 27 December 2017
Publication Date:
29 March 2018 (online)
![](https://www.thieme-connect.de/media/10.1055-s-00025476/201804/lookinside/thumbnails/1063_10-1055-s-0044-101453-1.jpg)
Abstract
Background and study aims Current endoscopic therapies for gastroesophageal reflux disorder (GERD) are limited by technical complexity, and/or cost. We sought to evaluate the success of a novel resection and plication (RAP) anti-reflux procedure.
Patients and methods RAP was performed on 10 patients with GERD refractory to proton pump inhibitor (PPI) therapy. RAP consists of semi-circumferential mucosectomy along with full-thickness plication of the lower esophageal sphincter (LES) and cardia. We assessed the technical success and safety as well as followed GERD-Health Related Quality of Life (GERD-HRQL) scores and medication usage.
Results All patients underwent RAP without adverse events and were discharged on the same day. Only half of the patients required general anesthesia. Follow-up ranged from 5 to 24 months (median 9 months) and all patients had a significant improvement in their GERD-HRQL scores (P < 0.0001, 95 % CI 19.3 – 25.3). 8 of 10 eliminated their daily PPI dependence.
Conclusions The RAP method has potential as an effective anti-reflux option. Its main advantages include a short procedure time, simple approach using readily available equipment, and possible avoidance of general anesthesia.
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