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Synthesis 1987; 1987(7): 662-664
DOI: 10.1055/s-1987-28043
DOI: 10.1055/s-1987-28043
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A New Method for the Synthesis of Pyridine and Pyrido[3,4-d]Pyridazine Derivatives
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Publikationsdatum:
20. August 2002 (online)
The reaction of equimolecular amounts of N′-(3-imino-1-alkenyl)hydrazones and dimethyl acetylenedicarboxylate affords functionalized 2(1H)-pyridinones. Treatment of these compounds with mineral acid or base yields the new 1,7-dioxo-1,2,6, 7-tetrahydropyrido[3,4-d]pyridazines.