Download PDF
Synlett 1990; 1990(2): 95-96
DOI: 10.1055/s-1990-20998
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

The Rhodium Carbenoid Route to Cyclic Ethers. Synthesis of the cis-2,7-Disubstituted Oxepane Skeleton of Isolaurepinnacin

Martin J. Davies* , Christopher J. Moody
  • *Department of Chemistry, Imperial College of Science, Technology & Medicine, London SW7 2AY, England
Further Information

Publication History

Publication Date:
08 March 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

The cis-2,7-disubstituted oxepane skeleton 1 of the marine natural product isolaurepinnacin is obtained by two routes, both of which involve a rhodium (II) acetate mediated cyclisation of a diazoalcohol to give a functionalised oxepane, suitable for further elaboration.