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Synlett 1991; 1991(2): 117-118
DOI: 10.1055/s-1991-20649
DOI: 10.1055/s-1991-20649
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The One-Pot Conversion of (Trichlorovinyl)amines into Ethynylenediamines
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Publication History
Publication Date:
07 March 2002 (online)
Treatment of N, N-disubstituted (trichlorovinyl)amines 1 with an equimolar mixture of butyllithium and lithium diorganoamides, prepared from the corresponding secondary amine and two equivalents of butyllithium, furnishes symmetrically and unsymmetrically substituted ethynylenediamines 4 (1,2-ethynediamines).