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Synlett 1991; 1991(4): 243-244
DOI: 10.1055/s-1991-20693
DOI: 10.1055/s-1991-20693
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ß-Lactams from Ester Enolates and Metalloimines: Synthesis and Reactivity of tert-Butyldimethylsilylimines
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Publication History
Publication Date:
07 March 2002 (online)
A new synthesis of N-tert-butyldimethylsilylimines from aldehydes is reported. Reaction of these reagents, prepared in situ, with lithium ester enolates affords in a one-pot procedure azetidinones protected as N-silyl derivatives.