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Synlett 1991; 1991(5): 345-346
DOI: 10.1055/s-1991-34740
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Selective Conversion of S-Protected Cysteine Derivatives to Cystine by Various Sulphoxide-Silyl Compound / Trifluoroacetic Acid Systems

Takaki Koide* , Akira Otaka, Hiromi Suzuki, Nobutaka Fujii
  • *Faculty of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto 606, Japan
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Publication Date:
07 March 2002 (online)

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Cystine formation from various S-protected cysteine derivatives by treatment with combinations of sulphoxides and silyl compounds in trifluoroacetic acid was examined, and selectivity of disulphide bond forming was found in these systems.