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Synlett 1991; 1991(10): 729-730
DOI: 10.1055/s-1991-34781
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Directed Alkylation of Phenols: A Convenient Synthesis of Highly Substituted Aromatic Rings

Matthew Gray* , Philip J. Parsons
  • *Department of Chemistry, University of Reading, Whiteknights, P.O. Box 224, Reading, Berkshire, RG6 2AD, England
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Publication Date:
13 March 2002 (online)

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A general route to 6-substituted salicylaldehydes from salicylaldehyde (2-hydroxybenzaldehyde) via the dianion 4 of salicylaldehyde aminal 3 [2-(2-hydroxyphenyl)-1,3-dimethylimidazolidine] is reported.