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Synlett 1992; 1992(1): 39-40
DOI: 10.1055/s-1992-21258
DOI: 10.1055/s-1992-21258
letter
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Selective Enzymatic Removal of Protecting Functions: Heptyl Esters as Carboxy Protecting Groups in Glycopeptide Synthesis
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Publikationsverlauf
Publikationsdatum:
18. September 2002 (online)
The selective C-terminal deprotection of acid- and base-labile multifunctional O-glycopeptide heptyl (Hep) esters is achieved under mild conditions (pH 7; 37 °C) by enzymatic hydrolysis with a lipase from Mucor javanicus.