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Synlett 1992; 1992(6): 497-498
DOI: 10.1055/s-1992-21391
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Reductions of α-Oxo N-Methoxy-N-methylamides: A Convenient Synthesis of 1,2-Diols

Mukund P. Sibi* , Rajiv Sharma
  • *Department of Chemistry, North Dakota State University, Fargo, North Dakota 58105-5516, USA
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Publication Date:
08 March 2002 (online)

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α-Oxo N-methoxy-N-methylamides 2 can be directly converted into 1,2-diols by excess sodium borohydride in ethanol at room temperature in high chemical yields.