PDF herunterladen
Synlett 1992; 1992(4): 332-334
DOI: 10.1055/s-1992-22004
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Metallocupration of Acetylenic Silyl Ketone: Synthesis and Reactivity of Polymetalated Functionalized Building Blocks

Alessandro Degl'Innocenti* , Enrico Stucchi, Antonella Capperucci, Alessandro Mordini, Gianna Reginato, Alfredo Ricci
  • *Centro C.N.R. Composti Eterociclici, via G. Capponi 9, I-50121 Firenze, Italy
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
08. März 2002 (online)

  als PDF herunterladen  Lizenzen und Reprints Alle Artikel dieser Rubrik

Treatment of ethynyl triphenylsilyl ketone (1) with stannylcuprates affords the corresponding bismetalated compounds. In particular, the use of tributylstannylcuprate as the Michael donor, allows fine tuning of the reactional polarity of the carbon at position 3 of the enonic framework. The intermediate cuprate can be further reacted in situ to afford an easy entry into the class of polyfunctionalized compounds such as exomethylenic 1,3-diketones 12, useful building blocks for natural product synthesis.