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Synlett 1993; 1993(1): 40
DOI: 10.1055/s-1993-22339
DOI: 10.1055/s-1993-22339
letter
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A Convenient Synthesis of 4-Alkylfuran-2-Acetic Acids
Further Information
Publication History
Publication Date:
19 March 2002 (online)
α-Chloroketones (2) are converted to 4-alkylfuran-2-acetic acids (1) by a 6-step procedure; the key transformation being regioselective ring opening of cyclic anhydrides (4) to form mono esters (5) exclusively.