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Synlett 1993; 1993(3): 217-218
DOI: 10.1055/s-1993-22408
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Total Stereocontrolled Synthesis of Lipoxin B4

Mouâd Alami* , Benoît Crousse, Gérard Linstrumelle, Lengo Mambu, Marc Larchevêque
  • *UR 402 du CNRS, Laboratoire de Chimie, Ecole Normale Supérieure, 24 rue Lhomond, F-75231 Paris Cedex 05, France
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Publication Date:
19 March 2002 (online)

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An efficient convergent synthesis of lipoxin B4 was achieved by coupling two chiral synthons : the diol 2 easily prepared from the acetylenic diol 4 and the allylic alcohol 3, followed by stereoselective reduction of the trienynetriol 10 with activated zinc.