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Synlett 1993; 1993(3): 229-230
DOI: 10.1055/s-1993-22413
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A New Easy One-Step Synthesis of Isoquinoline Derivatives from Substituted Phenylacetic Esters

A. Garcia Martínez* , A. Herrera Fern}ndez, D. Molero Vilchez, M. L. Laorden Gutiérrez, L. R. Subramanian
  • *Departamento de Química Org}nica, Facultad de Ciencias Químicas, Universidad Complutense, E-28040 Madrid, Spain
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Publication History

Publication Date:
19 March 2002 (online)

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The reaction of activated phenylacetic esters 1 with nitriles 3 in the presence of triflic anhydride easily affords 1-substituted 3-alkoxy isoquinolines 5 in good yields.