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Synlett 1993; 1993(7): 507-508
DOI: 10.1055/s-1993-22509
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Condensation of Dimethyl-3-methylglutaconate with Aldehydes: A One Pot Synthesis of Functionalized 5,6-Dihydro-(2H)-pyran-2-ones

Anne-Sophie Dussert* , Patrick Audin, Joëlle Paris
  • *Laboratoire de Chimie Thérapeutique, Faculté de Pharmacie, Université Claude Bernard, Lyon 1, 8 avenue Rockefeller, F-69373 Lyon Cedex 08, France
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Publication Date:
19 March 2002 (online)

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A straightforward method, providing α,β-unsaturated δ-lactones 1 bearing an ester group at γ-position (yields from 31 to 90%), is described.