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Synlett 1994; 1994(11): 933-934
DOI: 10.1055/s-1994-23053
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A Convenient One-Pot Procedure for N-Bromomethylation of Imide and Imide-Like Compounds

Ranjit C. Desai* , Robert P. Farrell, Gee-Hong Kuo, Dennis J. Hlasta
  • *Department of Medicinal Chemistry, Sterling Winthrop Pharmaceuticals Research Division, Sterling Winthrop Inc, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, USA
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Publication Date:
22 March 2002 (online)

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The one-pot synthesis of a variety of N-bromomethyl derivatives of imides and imide-like compounds using paraformaldehyde and 33 wt% solution of HBr in acetic acid is described.