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Synlett 1995; 1995(2): 142-144
DOI: 10.1055/s-1995-4901
DOI: 10.1055/s-1995-4901
letter
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The Enantioselective Synthesis of Neopentylamine Derivatives
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Publikationsverlauf
Publikationsdatum:
31. Dezember 2000 (online)
Enantiomerically pure neopentylamine derivatives 1 can be readily prepared from ketones 2 by a four step sequence involving imine formation with R-α-methylbenzylamine followed by a highly diastereoselective reduction with NaBH4.
enantioselective - amine - imine