PDF herunterladen
Synlett 1995; 1995(11): 1138-1140
DOI: 10.1055/s-1995-5194
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Diastereoselective Synthesis of Amino Acids Containing β-Quaternary Carbon Centers via Ester Enolate Claisen Rearrangement

Uli Kazmaier*
  • *Organisch-Chemisches Institut der Universität, Im Neuenheimer Feld 270, D-69120 Heidelberg, Germany
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
31. Dezember 2000 (online)

  als PDF herunterladen  Lizenzen und Reprints Alle Artikel dieser Rubrik

Ester enolate Claisen rearrangement of highly substituted glycine allylic esters allows the synthesis of sterically demanding amino acids with β-quaternary carbon centers. Because of the enolate fixation by chelation, the rearrangement occurs in a highly diastereoselective fashion.

Unsaturated amino acids - quaternary carbon centers - Claisen rearrangement - chelated enolate