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Synlett 1996; 1996(4): 389-391
DOI: 10.1055/s-1996-5416
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Selective O-Allylation of Amidoalcohols on Solid Support

Irina A. Motorina* , Florence Parly, David S. Grierson
  • *Institut de Chimie des Substances Naturelles, CNRS, 91198 Gif-sur-Yvette, France
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Publication History

Publication Date:
31 December 2000 (online)

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Selective O-allylation of non-activated primary alcohols in the presence of amide function is achieved by adsorption on the surface of chromatographic alumina. Microwave irradiation enhances considerably the rate of these reactions.

adsorbent - alumina - amidoalcohol - alkylation - selective