Solid Phase Synthesis of N-Alkyl Sulfonamides

Sharon M. Dankwardt; David B. Smith; John A. Porco Jr; Cindy H. Nguyen

doi:10.1055/s-1997-5776

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Synlett 1997; 1997(7): 854-856
DOI: 10.1055/s-1997-5776

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Solid Phase Synthesis of N-Alkyl Sulfonamides

Sharon M. Dankwardt¹ , David B. Smith¹ , John A. Porco Jr.² , Cindy H. Nguyen²

¹Roche Bioscience, Inflammatory Disease Unit, Parallel Synthesis Group, 3401 Hillview Ave, Palo Alto, California 94304
²Argonaut Technologies Inc., 887 Industrial Road, Suite G, San Carlos, California, 94070

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Publikationsdatum:
31. Dezember 2000 (online)

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Polymer-supported sulfonamides were alkylated using alkyl halides in the presence of DBU or with alcohols via the Mitsunobu reaction.

polymer-supported - solid-phase - sulfonamides - alkylation - Mitsunobu