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Synlett 1997; 1997(4): 371-372
DOI: 10.1055/s-1997-799
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Diisopropoxyaluminium Trifluoroacetate: A New off the Shelf Metal Alkoxide Type Reducing Agent for Reduction of Aldehydes and Ketones

K. G. Akamanchi* , N. R. Varalakshmy, B. A. Chaudhari
  • *Pharmaceutical Division, Department of Chemical Technology, University of Bombay, Matunga, Mumbai 400 019, India, Fax 91 22 414 5614
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Publication History

Publication Date:
31 December 2000 (online)

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A new off the shelf reducing agent, diisopropoxyaluminium trifluoroacetate, has been prepared by reacting aluminium isopropoxide with trifluoroacetic acid in dichloromethane. It is a white solid and stable when stored under dry conditions. Using this reagent various aldehydes and ketones have been reduced to the corresponding alcohols in moderate to quantitative yields, at room temperature in short time.

reduction - aluminium alkoxides - trifluoroacetic acid - aldehydes - ketones