Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000083.xml
Synlett 1997; 1997(8): 995-997
DOI: 10.1055/s-1997-934
DOI: 10.1055/s-1997-934
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.
A Novel Sm(II)-Induced Route to Highly Substituted Benzannulated Cyclooctanol Derivatives
Further Information
Publication History
Publication Date:
31 December 2000 (online)
![](https://www.thieme-connect.de/media/synlett/199708/lookinside/thumbnails/10.1055-s-1997-934-1.jpg)
Siloxycyclopropane derivatives 3 with a suitable styrene side chain can effectively be ring opened to precursors 2 which undergo reductive ring closure with SmI2 to furnish benzannulated cyclooctanols 1 or lactones 7 derived thereof. Tricyclic lactone 7c can be further substituted by conversion into a bridgehead enolate and reactions with electrophiles.
siloxycyclopropanes - samarium(II) iodide - Stille coupling - cyclooctanol - alkylation