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Synlett 1997; 1997(8): 935-938
DOI: 10.1055/s-1997-947
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Enantiomerically Pure 3-Substituted 2-Phenylprolines by Caesium Fluoride/Tetramethoxysilane Mediated 1,4-Addition of 3(S)-5(R)-Diphenylmorpholin-2-one to Acrylates

Laurence M. Harwood1 , Giles Hamblett2 , Antonio I. Jiménez-Díaz3 , David J. Watkin2
  • 1Department of Chemistry, Reading University, Whiteknights, READING RG6 6AD, U.K., Telephone +44 (0)1189 318449; Fax +44 (0)1189 316782; Email l.m.harwood@reading.ac.uk
  • 2Chemical Crystallography Laboratory, University of Oxford, Parks Road, OXFORD OX1 3PD, U.K.
  • 3Dyson Perrins Laboratory, University of Oxford, South Parks Road, OXFORD OX1 3QY, U.K.
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Publication History

Publication Date:
31 December 2000 (online)

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2-phenylproline - 2,5-diphenylmorpholin-2-one - Michael addition