RSS-Feed abonnieren
Bitte kopieren Sie die angezeigte URL und fügen sie dann in Ihren RSS-Reader ein.
https://www.thieme-connect.de/rss/thieme/de/10.1055-s-00000083.xml
Synlett 1997; 1997(10): 1193-1195
DOI: 10.1055/s-1997-989
DOI: 10.1055/s-1997-989
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.
One Flask Preparation of Trifluoromethylated Amides from Ketones and Trifluoromethyltrimethylsilane via Ritter Reaction with Nitriles
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
31. Dezember 2000 (online)
Trifluoromethylated amides are prepared in a simple one-flask reaction via the Ritter reaction of the corresponding trifluoromethylated silyl ethers, which themselves are readily obtained from the starting ketones and trifluoromethyltrimethylsilane. The yields are good to average.
Ritter reaction - (trifluoromethyl)trimethylsilane - trifluoromethylated tertiary amides - hydrolysis - acetonitrile