PDF herunterladen
Synlett 1998; 1998(6): 640-642
DOI: 10.1055/s-1998-1734
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Lanthanide Triflate Catalysed Reactions of Acetals with Primary Amines and Cascade Cyclisation Reactions

Harry Heaney* , Michael T. Simcox, Alexandra M. Z. Slawin, Robert G. Giles
  • *Department of Chemistry, Loughborough University, Loughborough, Leicestershire, LE11 3TU; Fax + 44(15 09)22 39 25; E-mail: h.heaney@lboro.ac.uk
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
31. Dezember 2000 (online)

  als PDF herunterladen  Lizenzen und Reprints Alle Artikel dieser Rubrik

The formation of imines from acetals and primary amines can be carried out at significantly lower temperatures using scandium or lanthanide triflates as catalysts, than in the absence of a catalyst: the intermediate aminol ethers can also take part in cascade cyclisation reactions, for example using tryptamine and ethyl tryptophanate.

acetal - re-usable catalyst - diastereoselectivity - imine - isoindolone