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Synlett 1998; 1998(8): 853-854
DOI: 10.1055/s-1998-1822
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A Convenient Way to N-Allyloxycarbonyl Protected Adenosine and Cytidine Derivatives

Sophie B. Heidenhain* , Yoshihiro Hayakawa
  • *Laboratory of Bioorganic Chemistry, Graduate School of Human Informatics, Nagoya University, Chikusa, Nagoya 464-01, Japan; Fax + 81-52-789-4848; E-mail: yoshi@info.human.nagoya-u.ac.jp
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Publication History

Publication Date:
31 December 2000 (online)

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A convenient method for the introduction of an allyloxycarbonyl protector to adenyl and cytosyl bases using commercially available allyloxycarbonyl chloride as the protecting reagent has been developed.

allyloxycarbonyl chloride - allyloxycarbonyl protector - N-methylimidazole - nucleoside 3′-phosphoramidite