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Synlett 1998; 1998(9): 985-986
DOI: 10.1055/s-1998-1849
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Synthesis of 8-(Mannosyloxy)adenosine: a Novel Nucleoside-Carbohydrate Hybrid

Hideyuki Sugimura* , Kevin Stansfield
  • *The Noguchi Institute, 1-8-1, Kaga, Itabashi-Ku, Tokyo 173, Japan
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Publikationsdatum:
31. Dezember 2000 (online)

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As a basic study directed towards the synthesis of guanofosfocin analogues, a new class of nucleoside-carbohydrate hybrid has been prepared by glycosylation of 8-oxoadenosine derivatives with mannopyranosyl bromide in the presence of silver carbonate.

guanofosfocin - glycosylation - 8-oxoadenosine - mannosyl bromide - silver carbonate