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Synlett 1999; 1999(11): 1802-1804
DOI: 10.1055/s-1999-2930
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Application of a Ring Closing Metathesis Based Linker to the Solid Phase Synthesis of Oligosaccharides

Laurent Knerr* , Richard R. Schmidt
  • *Fakultät Chemie, Universität Konstanz, Fach M 725, D-78457 Konstanz, Germany; Fax +49/75 31/88 31 35
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Publication Date:
31 December 1999 (online)

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A linker allowing a ring closing metathesis mediated cleavage of resin bound oligosaccharides in the form of their 1-O-allyl derivatives was designed. This new linker system for the solid phase synthesis of oligosaccharides via the trichloroacetimidate approach demonstrated highly promising results.

solid phase synthesis - oligosaccharides - linker - ring closure metathesis