Download PDF
Synlett 1999; 1999(11): 1781-1783
DOI: 10.1055/s-1999-2946
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Selective Monoalkylation of Ammonia: A High Throughput Synthesis of Primary Amines

Sukanta Bhattacharyya* , Kurt A. Neidigh, Mitchell A. Avery, John S. Williamson
  • *Department of Chemistry, The University of Mississippi, University, MS 38677, USA
Further Information

Publication History

Publication Date:
31 December 1999 (online)

  PDF Download  Permissions and Reprints All articles of this category

Primary amines are obtained in good to excellent yields by highly selective monoalkylation of ammonia with alkyl and aryl ketones using titanium(IV) isopropoxide and sodium borohydride.

primary amines - reductive amination - titanium(IV) isopropoxide