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Synlett 1999; 1999(12): 2007-2022
DOI: 10.1055/s-1999-2988
new tools in synthesis
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Organic Synthesis Supported by Antibody Catalysis

Jens Hasserodt*
  • *Department of Chemistry, The Scripps Research Institute, La Jolla, California, USA
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Publikationsdatum:
31. Dezember 1999 (online)

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Catalytic antibody research has provided a remarkable number of catalyzed reactions since it was begun thirteen years ago. This paper introduces a few antibody-catalyzed reactions that may be of particular interest to the organic synthetic chemist. It also gives a short introduction into the production of hapten-binding monoclonal antibodies and modern improvements for catalyst discovery.

biocatalysis - catalytic antibodies - aldol reactions - pericyclic reactions - cationic olefin cyclizations - kinetic racemate resolution