Synlett 2000; 2000(9): 1275-1276
DOI: 10.1055/s-2000-7141
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

A Mild and Selective Cleavage of Tritylethers by Cerium(III) Chloride

J. S. Yadav* , B. V. Subba Reddy
  • *Organic Division-I, Indian Institute of Chemical Technology, Hyderabad-500 007, India; E-mail: yadav@iict.ap.nic.in
Further Information

Publication History

Publication Date:
31 December 2000 (online)

  PDF Download  Permissions and Reprints All articles of this category

Trityl ethers are selectively cleaved by cerium(III) chloride in high yields in refluxing acetonitrile under neutral reaction conditions. The method is compatible with other acid sensitive functional groups like acetonide, acetate, benzoate, BOC, Cbz, benzyl, TBDPS, PMB, allyl, methyl and tetrahydropyranyl ethers present in the molecule.

cerium(III) chloride - trityl ethers - alcohols