PDF herunterladen
Synlett 2001; 2001(4): 0553-0556
DOI: 10.1055/s-2001-12318
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Gram Scale-up Synthesis of all-(Z)-Cyclododecatetraene: A Comparison between Intramolecular Wittig and Ring Closing Metathesis Approaches

Sophie Guiard* , Maurice Santelli, Jean-Luc Parrain
  • *Laboratoire de Synthèse Organique associé au CNRS (UMR 6009), Faculté des Sciences de Saint Jérôme, Avenue Escadrille Normandie-Niemen, 13397 Marseille Cedex 20, France; E-mail: jl.parrain@lso.u-3mrs.fr
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
31. Dezember 2001 (online)

  als PDF herunterladen  Lizenzen und Reprints Alle Artikel dieser Rubrik

A total synthesis of all-(Z)-cyclododeca-1,4,7,10-tetraene was achieved in 28% overall yield using an intramolecular Wittig reaction as key step while an approach based on ring closing metathesis was found ineffective.

all-(Z)-cyclododeca-1,4,7,10-tetraene - intramolecular Wittig reaction - ring closing metathesis - tetradecapenta-1,4,7,10,13-ene