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Synlett 2001; 2001(7): 1191-1193
DOI: 10.1055/s-2001-15147
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New Palladium-Catalysed Access to 3-(1'-Indanylidene) Phthalide, Precursor of the Core of Fredericamycin A

Didier Bouyssi* , Geneviève Balme
  • *Laboratoire de chimie organique 1, associé au CNRS, Université Claude Bernard Lyon 1, CPE, 43 Bd du 11 Novembre 1918, 69622 Villeurbanne, France; Fax 33.4.72.43.12.14; E-mail: balme@univ-lyon1.fr
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Publication Date:
31 December 2001 (online)

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An efficient synthesis of 3-(1'-indanilydene) phthalide is described via a palladium-catalysed biscyclisation step.

palladium - cyclisation - tandem reaction - heterocycle - lactone