RSS-Feed abonnieren
Bitte kopieren Sie die angezeigte URL und fügen sie dann in Ihren RSS-Reader ein.
https://www.thieme-connect.de/rss/thieme/de/10.1055-s-00000084.xml
Synthesis 2001(10): 1509-1512
DOI: 10.1055/s-2001-16088
DOI: 10.1055/s-2001-16088
PAPER
© Georg Thieme Verlag Stuttgart · New York
Microwave-Assisted Solid-Support Synthesis of Pyrazolino/Iminopyrimidino/Thioxopyrimidino Imidazolines
Weitere Informationen
Received
9 January 2001
Publikationsdatum:
29. September 2004 (online)
Publikationsverlauf
Publikationsdatum:
29. September 2004 (online)
![](https://www.thieme-connect.de/media/synthesis/200110/lookinside/thumbnails/10.1055-s-2001-16088-1.jpg)
Abstract
An expeditious solvent-free synthesis of pyrazolino/iminopyrimidino/thioxopyrimidino imidazoline derivatives from readily accessible oxazolones on solid support using microwaves is described. The reaction time has been brought down from hours to minutes with improved yield as compared to conventional heating.
Key words
microwave irradiation - solid-support synthesis - heterocycles
- 1
Gedye R.Smith F.Westaway K.Ali H.Baldisera L.Laberge L.Rousell J. Tetrahedron Lett. 1986, 27: 279 - 2
Giguere RJ.Bray TL.Duncan SM. Tetrahedron Lett. 1986, 27: 4945 - 3
Caddick S. Tetrahedron 1995, 10403 - 4
Loupy A.Petit A.Hamelin J.Taxier BF.Jacqualt P.Matha D. Synthesis 1998, 1213 - 5
Deshayas S.Marion L.Loupy A.Lucha JL.Petit A. Tetrahedron Lett. 1999, 55: 10851 - 6
Dittmer DC. Chem. Ind. 1997, 779 - 7
El-Magharaby A.Abou El-ElaA.Khalafolla AK.El-Shawi E. J. Indian Chem. Soc. 1985, 62: 676 -
8a
Girges MM.El-Zahab MMA.Hanna MA. Collect. Czech. Chem. Commun. 1989, 54: 1096 - 9
Singh R.Pandey VK.Srimal RC. Indian J. Pharm. Sci. 1992, 54: 4 -
10a
Emeric G,Hott J, andPerez J. inventors; PCT Int. Appl. WO 9602,538. -
-
11a
Blythin DJ. inventors; Eur. Pat. Appl. 29934. -
- 12
Rani HS.Mogilaian K.Sreehivasulu B. Indian J. Heterocycl. Chem. 1995, 5: 45 - 13
Kidwai M.Bhushan KR.Sapra P.Saxena RK.Singh M. Bioorg. Med. Chem. 2000, 8: 69 - 14
Kidwai M.Sapra P.Bhushan KR.Saxena RK.Singh M. Montash. Chem. 2000, 131: 85 - 15
Kidwai M.Dave B.Misra P.Saxena RK.Singh M. Inorg. Chem. Commun. 2000, 3: 465 - 16
Kidwai M.Misra P.Dave B. Main Group Met. Chem. 2000, 23: 401 - 17
Cativiela C.Melendez E. Synthesis 1978, 832 - 18
Bram G.Decodts G. Tetrahedron Lett. 1980, 21: 5011 - 19
Molina P.Almendros P.Fresneda PM. Tetrahedron 1994, 50: 2241 - 20
Karplus M. J. Chem. Phys. 1959, 30: 11 - 22
Bram G.Loopy A.Majdoub M. Tetrahedron 1990, 46: 5167
References
Aluminium Oxide Basic, Brockmann I (Aldrich Chem. Co., Cat. No. 19, 944-3, ~150 mesh, 58 Å, Surface area 155 m2/g)was used. Alumium Oxide Neutral, Brockmann I (Aldrich Chem. Co., Cat. No. 19, 997-4, ~150 mesh, 58 Å, Surface area 155 m2/g)was used.