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Synlett 2001; 2001(9): 1419-1420
DOI: 10.1055/s-2001-16796
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Synthesis of a Water Soluble Carborane Containing Amino Acid as a Potential Therapeutic Agent

Bhaskar C. Das* , Sasmita Das, Guishing Li, Weiliang Bao, George W. Kabalka
  • *Department of Chemistry and Radiology, The University of Tennessee, Knoxville, Tennessee 37996-1600 USA; Fax (865) 974-2997; E-mail: kabalka@utk.edu
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Publikationsdatum:
28. August 2001 (online)

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A novel water soluble amino acid, 1-amino-3-[2-[7-(6-deoxy-α/β-galactopyranos-6-yl)-1,7-dicarba-closo-dodecarboran(12)-1-yl]ethyl]cyclobutanecarboxylic acid, has been developed as a potential therapeutic agent for use in neutron capture therapy.

BNCT - sugar - amino acid - carborane - therapeutic agent