PDF herunterladen
Synlett 2001; 2001(11): 1805-1807
DOI: 10.1055/s-2001-18105
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

An Efficacious Synthetic Strategy for cis-Clerodane Diterpenoids. Application to the Total Synthesis of (±)-6β-Acetoxy-2-oxokolavenool

Hsing-Jang Liu* , Yun-Lung Ho, Jen-Dar Wu, Kak-Shan Shia
  • *Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan 30013, R.O.C.; Fax + 886(3)5 72 07 11; E-mail: hjliu@mx.nthu.edu.tw
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
29. Oktober 2001 (online)

  als PDF herunterladen  Lizenzen und Reprints Alle Artikel dieser Rubrik

An efficient synthetic strategy for cis-clerodane diterpenoids has been developed. The key ingredient is the face selective Diels-Alder reaction of dienophile 8. The successful application of this strategy has culminated in the total synthesis of the naturally occurring compound 6β-acetoxy-2-oxokolavenool in racemic form.

reductive alkylation - α-cyano ketones - total synthesis - cis-clerodanes