Planta Med 2001; 67(8): 778-780
DOI: 10.1055/s-2001-18346
Letter

© Georg Thieme Verlag Stuttgart · New York

A Reversed Phase High Performance Liquid Chromatography Method for the Analysis of Boswellic Acids in Boswellia serrata

Markus Ganzera1 , Ikhlas A. Khan1, 2,*
  • 1 National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, The University of Mississippi, University, Mississippi, USA
  • 2 Department of Pharmacognosy, School of Pharmacy, The University of Mississippi, University, Mississippi, USA
Further Information

Publication History

November 3, 2000

January 21, 2001

Publication Date:
09 November 2001 (online)

Abstract

An HPLC method for the separation of boswellic acids, the active constituents in Boswellia serrata resin has been developed. The first accurate determination of 6 individual acids was possible in the resin as well as in multi-component preparations. By using an acidic mobile phase, raised temperature and a 4 μm Synergi MAX-RP 80 Å column the acids could be detected at levels as low as 0.9 μg/ml. The study of market products revealed significant variations in the content of these pharmacologically active compounds in commercial samples.

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Dr. Ikhlas A. Khan

NCNPR

University of Mississippi

University

MS 38677

USA

Phone: +1-662-915-7821

Fax: +1-662-915-7989

Email: rikhan@olemiss.edu