Albumin Binding Capacity (ABiC) is reduced in commercially available Human Serum Albumin preparations with stabilizers

S. Klammt; B. Brinkmann; S. Mitzner; E. Munzert; J. Loock; J. Stange; J. Emmrich; S. Liebe

doi:10.1055/s-2001-919056

Zeitschrift für Gastroenterologie, Table of Contents

Z Gastroenterol 2001; 39: 24-27
DOI: 10.1055/s-2001-919056

Supplement

Albumin Binding Capacity (ABiC) is reduced in commercially available Human Serum Albumin preparations with stabilizers

S. Klammt² , B. Brinkmann² , S. Mitzner² , E. Munzert¹ , J. Loock² , J. Stange² , J. Emmrich² , S. Liebe¹

¹Dept. of Internal Medicine, University of Rostock, Germany
²TERAKLIN AG, Rostock, Germany

Abstract

Full Text

References

1 Pugh R N, Murray-Lyon I M, Dawson J L, Pietroni M C, Williams R. Transection of the oesophagus for bleeding oesophageal varices. Br J Surg. 1973; 60 646-649
2 Cooper G S, Bellamy P, Dawson N V, Desbiens N. A prognostic model for patients with end-stage liver disease. Gastroenterology. 1997; 113 1278-1288
3 Knaus W A, Draper E A, Wagner D P, Zimmerman J E. APACHE II: a severity of disease classification system. Crit Care Med. 1985; 13 818-829
4 Sudlow G, Birkett D J, Wade D N. Further characterization of specific drug binding sites on human serum albumin. Mol Pharmacol. 1976; 12 1052-1061
5 Sudlow G, Birkett D J, Wade D N. The characterization of two specific drug binding sites on human serum albumin. Mol Pharmacol. 1975; 11 824-832
6 Carter D C, Ho J X. Structure of serum albumin. Adv Protein Chem. 1994; 45 153-203
7 Fehske K J, Müller W E, Wollert U. Commentary The Location Of Drug Binding Sites In Human Serum Albumin. Biochem Pharmacol. 1981; 30 687-692
8 Kragh-Hansen U. Structure and ligand binding properties of human serum albumin. Dan Med Bull. 1990; 37 57-84
9 Peters T. All about albumin. San Diego, Ca; Academic Press Inc 1996
10 Peters Jr T. Serum albumin. Adv Protein Chem. 1985; 37 161-245
11 Brodersen R. Binding of Bilirubin and other ligands to human serum albumin. Peters T and Sjöholm I Albumin: Structure, Biosynthesis and Function Pergamon Press 1977: 61-70.
12 Banagale R C, Bernstein L H. Reserve bilirubin binding capacity measured by absorbance deviation at saturation of primary albumin binding sites. Res Commun Chem Pathol Pharmacol. 1982; 38 463-479
13 Burckart G J, Whitington P F, Gross S R. Reserve bilirubin binding capacity determined by difference spectroscopy. i. modifications and performance of the difference spectroscopy assay. J Pediatr Gastroenterol Nutr. 1982; 1 489-493
14 Whitington P F, Burckart G J, Gross S R, Korones S B, Helms R A. Alterations in reserve bilirubin binding capacity of albumin by free fatty acids. ii. in vitro and in vivo studies using difference spectroscopy. J Pediatr Gastroenterol Nutr. 1982; 1 495-501
15 Kragh-Hansen U. Octanoate binding to the indole - and benzodiazepine binding region of human serum albumin. Biochem J. 1991; 273 641-644 (S 02)
16 Brodersen R, Hansen P. Bilirubin displacing effect of stabilizers added to injectable preparations of human serum albumin. Acta Paediatr Scand. 1977; 66 133-135
17 Ebbesen F, Brodersen R. Comparison between two preparations of human serum albumin in treatment of neonatal hyperbilirubinaemia. Acta Paediatr Scand. 1982; 71 85-90

Sebastian Klammt

Rostock

Email: sebastian.klammt@medizin.uni-rostock.de