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Planta Med 2002; 68(1): 66-67
DOI: 10.1055/s-2002-19866
Letter

© Georg Thieme Verlag Stuttgart · New York

Methyl Psilalate: A New Antimicrobial Metabolite from Psila boliviensis

Silvia Erazo1 , Rosa Negrete1 , Mercedes Zaldívar2 , Nadine Backhouse1 , Carla Delporte1 , Irina Silva1 , Eliana Belmonte3 , José Luis López-Pérez4 , Arturo San Feliciano4
  • 1Department of Pharmacological and Toxicological Chemistry, School of Chemical and Pharmaceutical Sciences, University of Chile, Santiago, Chile
  • 2Department of Biochemistry and Molecular Biology, School of Chemical and Pharmaceutical Sciences, University of Chile, Santiago, Chile
  • 3Department of Archeology and Museumology, Faculty of Social, Administrative and Economical Science, University of Tarapacá, Arica, Chile
  • 4Department of Organic and Pharmaceutical Chemistry, Faculty of Pharmacy, University of Salamanca, Salamanca, Spain
Further Information

Publication History

January 26, 2001

March 24, 2001

Publication Date:
31 January 2002 (online)

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Abstract

Psila boliviensis (Wedd.) Cabr. yielded a new phenylpropanoid, named methyl psilalate. The structure was established by means of standard spectroscopic techniques. The microbiological evaluation of the compound revealed antibacterial activity against Gram-positive and Gram-negative bacteria.

References

  • 1 Marticorena C, Quezada M. Flora Vascular de Chile.  Gayana. 1985;  42 29
    PubMedSearch in Google Scholar
  • 2 Castro M, Villagran C, Kalin M T. Estudio Etnobotánico en la Precordillera y Altiplano de los Andes del Norte de Chile (18°-19°S).  Volumen en síntesis - Proy MAB-6-UNEP-UNESCO Santiago de Chile. 1982;  II 133-205
    PubMedSearch in Google Scholar
  • 3 Zdero C, Bohlmann F, Solomon J C, King R M, Robinson H. Ent-clerodanes and other constituents from Bolivian Baccharis species.  Phytochemistry. 1989;  28 531-42
    CrossrefPubMedSearch in Google Scholar
  • 4 Morales G, Mancilla A, Gallardo O, Trujillo R, Loyola L, Breton J L. Diterpenoids and flavonoids from Baccharis boliviensis .  Boletín Sociedad Chilena de Química. 1990;  3 257-63
    PubMedSearch in Google Scholar
  • 5 Marhuenda E, García M D. Mise en evidence des propriétés antimicrobiennes des sommites fleuries D’Ononis natrix L. Identification de l’ acide férulique.  Plantes Médicinales et Phytothérapie. 1985;  19 163-72
    PubMedSearch in Google Scholar
  • 6 García M D, Marhuenda E. Isolement et activité antimicrobienne de l’acide vanillique et de l’acide p-hydroxybenzoique, constituants D’Ononis natrix .  Fitoterapia. 1985;  56 349-50
    PubMedSearch in Google Scholar
  • 7 Binutu O A, Adesogan K E, Okogun J I. Antibacterial and antifungal compounds from Kigelia pinata .  Planta Medica. 1996;  62 352-3
    Thieme ConnectPubMedSearch in Google Scholar
  • 8 Palacios P, Gutkind G, Rondina R, De Torres R, Coussio J D. Antimicrobial activity of Baccharis crispa and Baccharis notosergila .  Planta Medica . 1983;  49 128
    PubMedSearch in Google Scholar
  • 9 Rahalison L, Hamburger M, Hostettmann K, Monod M, Frenk E. A bioautographic agar overlay method for detection of antifungal compounds from higher plants.  Phytochemical Analysis. 1991;  2 199-203
    PubMedSearch in Google Scholar

Dr. Silvia Erazo

Department of Pharmacological and Toxicological Chemistry

School of Chemical and Pharmaceutical Sciences

University of Chile

P.O. Box 233

Santiago-1

Chile

Email: serazo@uchile.cl

Fax: 56-2-2227900