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Synlett 2002(4): 0625-0627
DOI: 10.1055/s-2002-22701
LETTER
© Georg Thieme Verlag Stuttgart · New York

Highly Convenient and Efficient One-pot Conversions of Aldehydes into Nitriles and Ketones into Amides Using HY-Zeolite [1]

K. V. N. S. Srinivas, E. Bolla Reddy, Biswanath Das*
Organic Chemistry Division-I, Indian Institute of Chemical Technology, Hyderabad-500 007, India
Fax: +91(40)7173387; e-Mail: biswanathdas@yahoo.com;
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Publikationsverlauf

Received 14 January 2002
Publikationsdatum:
05. Februar 2007 (online)

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Abstract

One-pot conversions of aldehydes into nitriles and ketones into amides have been carried out conveniently and efficiently using HY-zeolite as catalyst. Both microwave irradiation and conventional methods have been studied.

Key words

aldehydes - ketones - nitriles - amides - HY-zeolite - microwave irradiation

    References

  • 1a

    Part 13 in the series, „Studies on Novel Synthetic Methodologies”, for part 12 see: Ravindranath, N.; Ramesh, C.; Das, B. Synlett 2002, submitted.

  • 1b

    IICT Communication No. 4325.

  • 2a Diana GD. Cutcliffe D. Volkots DL. Mallamo JP. Bailey TR. Vescio N. Oglesley RC. Nitz TJ. Wetzel J. Girandu V. Pevear DC. Dutko FJ. J. Med. Chem.  1993,  36:  3240 
    CrossrefSuche in Google Scholar
  • 2b Chihiro M. Nagamoto H. Takemura I. Kitano K. Komatsu H. Sekiguchi K. Tabusa F. Mori T. Tominnaga M. Yabuuchi Y. J. Med. Chem.  1995,  38:  353 
    CrossrefSuche in Google Scholar
  • 2c Fabiani ME. Drug News Perspect.  1999,  12:  207 
    CrossrefSuche in Google Scholar
  • 2d Khanna IK. Weier RM. Yu Y. Xu XD. Koszyk FJ. Callins PW. Kobaldt CM. Veenhuizen AW. Perkins WE. Casler JJ. Masferrer JL. Zhung YY. Gregory SA. Seibert K. Isakson PC. J. Med. Chem.  1997,  40:  1634 
    CrossrefSuche in Google Scholar
  • 3a Cohen MA. Sawden J. Turner NJ. Tetrahedron Lett.  1990,  31:  7223 
    CrossrefSuche in Google Scholar
  • 3b Yamada H. Chimia  1993,  47:  69 
    CrossrefSuche in Google Scholar
  • 3c Crossby J. Moiller J. Parratt JS. Turner NJ. J. Chem. Soc., Perkin Trans. 1  1994,  1679 
    Crossref
  • 3d Luo F.-T. Jeevanandam A. Tetrahedron Lett.  1998,  39:  9455 
    CrossrefSuche in Google Scholar
  • 4 March J. Advanced Organic Chemistry   John Wiley and Sons; New York: 1992.  p.1038 ; and references cited therein
  • 5 Wang EC. Lin G.-J. Tetrahedron Lett.  1998,  36:  4047 ; and references cited therein
    Suche in Google Scholar
  • 6a Feng J.-C. Lin G. Dia L. Bian N.-S. Synth. Commun.  1998,  28:  3765 
    Thieme ConnectSuche in Google Scholar
  • 6b Bose DS. Narsaiah AV. Tetrahedron Lett.  1998,  39:  6533 
    Thieme ConnectSuche in Google Scholar
  • 6c Das B. Madhusudhan P. Venkataiah B. Synlett  1999,  1569 
    Thieme Connect
  • 6d Das B. Ramesh C. Madhusudhan P. Synlett  2000,  1599 
    Thieme Connect
  • 7 Sosnovsky G. Krogh JA. Umhoefer SG. Synthesis  1979,  722 
    Thieme Connect
  • 8 Webb KS. Levy D. Tetrahedron Lett.  1995,  36:  5117 
    CrossrefSuche in Google Scholar
  • 9 Marouka K. Yamamoto H. In Comprehensive Organic Synthesis   Vol. 6:  Trost BM. Pergamon Press; Oxford: 1991.  p.763 
    Suche in Google Scholar
  • 10a Olah GA. Fung AP. Synthesis  1979,  537 
  • 10b Gawly RE. Org. React.  1988,  35:  1 
    Suche in Google Scholar
  • 11 Meshram HM. Synth. Commun.  1990,  20:  3253 ; and references cited therein
    CrossrefSuche in Google Scholar
  • 12a Novotny A. inventors; U.S. Patent  2569114.  ; Chem. Abstr. 1952, 46, 5078
  • 12b Novotny A. inventors; U.S. Patent  2579851.  ; Chem. Abstr. 1952, 46, 6668
  • 12c Barnett C, Cohn IM, and Lincoln J. inventors; U.S. Patent  2754298.  ; Chem. Abstr. 1957, 51, 2853
  • 12d Delgado F. Cano AC. Garcia O. Alvarado J. Velasco L. Alvarez C. Rudler H. Synth. Commun.  1992,  22:  2125 
    Suche in Google Scholar
  • 12e Lavrent A. Jacquault P. Di Martino J.-L. Hamelin J. J. Chem. Soc., Chem. Commun.  1995,  1101 
  • 12f Das B. Ravindranath N. Venkataiah B. Madhusudhan P. J. Chem. Res., Synop.  2000,  482