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Synthesis 2003(8): 1157-1159
DOI: 10.1055/s-2003-39395
DOI: 10.1055/s-2003-39395
SHORTPAPER
© Georg Thieme Verlag Stuttgart ˙ New York
Effective Fluorination Reaction with Et3N˙3HF Under Microwave Irradiation
Weitere Informationen
Received
14 February 2003
Publikationsdatum:
26. Mai 2003 (online)
Publikationsverlauf
Publikationsdatum:
26. Mai 2003 (online)

Abstract
Fluorination reaction of epoxides and alkyl mesylates can be effectively achieved by reaction with Et3N˙3HF under microwave irradiation. The reaction time could be greatly reduced compared to the reaction under thermal conditions. The reactions were completed in a few minutes and the use of large excess of reagents could be avoided.
Key words
microwave irradiation - epoxides - fluorination - ring opening - Et3N˙3HF
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