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Synthesis 2003(8): 1267-1271
DOI: 10.1055/s-2003-39410
DOI: 10.1055/s-2003-39410
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York
Zr(NO3)4: A Versatile Oxidizing Agent for Aromatization of Hantzsch 1,4-Dihydropyridines and 1,3,5-Trisubstituted Pyrazolines [1]
Further Information
Received
20 February 2003
Publication Date:
26 May 2003 (online)
Publication History
Publication Date:
26 May 2003 (online)
Abstract
An efficient oxidative aromatization of Hantzsch 1,4-dihydropyridines and 1,3,5-trisubstituted pyrazolines to the corresponding pyridines and pyrazoles has been reported using Zr(NO3)4 in acetic acid at ambient temperature. The reactions are very fast and the products were isolated in high yields and in pure form.
Key words
1,4-dihydropyridines - pyrazolines - Zr(NO3)4 - aromatization
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IICT Communication No. 030205.