Synlett 2003(11): 1719-1721
DOI: 10.1055/s-2003-41008
LETTER
© Georg ThiemeVerlag Stuttgart ˙ New York

Efficient Synthesis of (±)-Dihydrorhipocephalin,a Bioactive Terpenoid from Caribbean Marine Algae of the Genera Penicillus and Udotea

Laurent Commeirasa, Robert Vallsb, Maurice Santellia, Jean-Luc Parrain*a
a Laboratoire de Synthèse au Organiqueassocié CNRS (UMR 6009), Faculté desSciences de Saint Jérôme, AvenueEscadrille Normandie-Niemen, 13397 Marseille Cedex 20,France
e-Mail: jl.parrain@univ.u-3mrs.fr;
b Laboratoire des Organophosphorés associé auCNRS (UMR 6009), Faculté des Sciencesde Saint Jérôme, Avenue Escadrille Normandie-Niemen,13397 Marseille Cedex 20, France
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Publication History

Received 26 May 2003
Publication Date:
11 August 2003 (online)

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Abstract

The first total synthesis of (±)-dihydrorhipocephalin fromCaribbean marine algae of the genera Penicillus and Udotea was accomplished, in few steps,controlling the construction of 2-substituted 1,4-diacetoxybutadienemoiety and the configuration of the central double bond.