
Abstract
A biologically monitored fractionation of the resinous exudate extract of Haplopappus foliosus DC. is reported. Purification of the two active fractions yielded 2-α-hydroxy-cis-cleroda-3,13(Z),8(17)-trien-15-oic acid (1) and 2-α-acetoxy-cis-cleroda-3,13(Z),8(17)-trien-15-oic acid (2), two new clerodane diterpenes.
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Prof. Dr. René Torres
Department of Basic Chemistry
University of Santiago of Chile
Casilla 40
Correo 33
Santiago of Chile
Chile
Email: aurzuamoll44@yahoo.com