Abstract
A father and his daughter displayed strictly similar focal brain dysplasia at MR examination, characterized by regional medial posterior laminar sub-cortical grey matter heterotopia. To our knowledge, no family presenting such anomalies has yet been described. LIS1 and DCX gene defects were excluded. Collecting patients with such inherited dysplasia should improve our knowledge of the genetic basis of cortical malformations.
Key words
Brain Malformation - Heterotopia - Mental Deficiency - Epilepsy
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G. Sébire
Service de Neurologie Pédiatrique, CHU Fleurimont, Université de Sherbrooke
3001 12ème Av. Nord
J1H 5N4, Sherbrooke
Canada
Email: gsebire@compuserve.com
