RSS-Feed abonnieren
Bitte kopieren Sie die angezeigte URL und fügen sie dann in Ihren RSS-Reader ein.
https://www.thieme-connect.de/rss/thieme/de/10.1055-s-00000084.xml
Synthesis 2003(13): 2027-2032
DOI: 10.1055/s-2003-41449
DOI: 10.1055/s-2003-41449
PAPER
© Georg Thieme Verlag Stuttgart · New York
Synthesis of 2,3-Disubstituted 5,6,7,8-Tetrahydronaphthyls and Related Structures via Diels-Alder Reaction
Weitere Informationen
Received
27 March 2003
Publikationsdatum:
10. September 2003 (online)
Publikationsverlauf
Publikationsdatum:
10. September 2003 (online)
Abstract
A variety of 2,3-disubstituted 5,6,7,8-tetrahydronaphthyl analogues have been synthesized via vinylation of cyclic ketones, subsequent lactonisation and thermally induced, inverse electron demand hetero Diels-Alder reaction. The diversity of the obtained products derives from the multiplicity of cyclic ketones and from the variety of dienophiles of the Diels-Alder reaction.
Key words
condensation - ketones - lactones - bicyclic compounds - Diels-Alder reaction
- 1
Ammenn J,Paal M,Ruehter G,Schotten T, andStenzel W. inventors; PCT Int. Appl. WO 0078724. ; Chem Abstr. 2001, 134, P 56669c -
2a
Boger DL.Mullican MD. Tetrahedron Lett. 1982, 23: 4551 -
2b
Boger DL.Mullican MD. Tetrahedron Lett. 1982, 23: 4555 -
2c
Boger DL.Patel M.Mullican MD. Tetrahedron Lett. 1982, 23: 4559 -
2d
Grunewald GL.Sall DJ.Monn JA. J. Med. Chem. 1988, 31: 433 - 3
Boger DL.Brotherton CE. J. Org. Chem. 1984, 49: 4050 - 5
Argade AB.Joglekar BR. Synth. Commun. 1993, 23: 1979 - 6
Boger DL.Mullican MD. Org. Synth. 1987, 65: 98 - 7
Diez-Barra A.De La Hoz A.Diaz-Ortiz A.Prieto P. Synlett 1992, 893
References
Commercially available from Fluka.